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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM2
All Species:
32.87
Human Site:
T384
Identified Species:
51.65
UniProt:
P31350
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31350
NP_001025.1
389
44878
T384
S
P
T
E
N
S
F
T
L
D
A
D
F
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100144
351
40744
Dog
Lupus familis
XP_540076
394
45449
T389
S
P
T
E
N
S
F
T
L
D
A
D
F
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P11157
390
45077
T385
N
S
T
E
N
S
F
T
L
D
A
D
F
_
_
Rat
Rattus norvegicus
Q4KLN6
390
45020
T385
N
S
T
E
N
S
F
T
L
D
A
D
F
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506085
394
45462
T389
S
S
T
E
N
S
F
T
L
D
A
D
F
_
_
Chicken
Gallus gallus
XP_419948
384
44421
T379
K
P
T
D
N
S
F
T
L
D
A
E
F
_
_
Frog
Xenopus laevis
NP_001080772
386
44577
T381
K
P
K
D
N
T
F
T
L
D
A
D
F
_
_
Zebra Danio
Brachydanio rerio
P79733
386
44575
T381
G
T
T
D
N
T
F
T
L
D
A
D
F
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48592
393
45096
T388
N
P
L
D
N
V
F
T
L
D
A
D
F
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42170
381
44271
D376
N
E
A
E
R
Q
F
D
L
E
A
D
F
_
_
Sea Urchin
Strong. purpuratus
XP_780110
412
47263
K402
S
T
N
S
S
T
K
K
Q
H
T
F
S
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6Y657
333
38312
Baker's Yeast
Sacchar. cerevisiae
P09938
399
46129
G391
K
S
T
K
Q
E
A
G
A
F
T
F
N
E
D
Red Bread Mold
Neurospora crassa
Q9C167
410
46679
D392
S
T
K
K
A
D
A
D
A
E
V
A
K
N
E
Conservation
Percent
Protein Identity:
100
N.A.
72.4
95.4
N.A.
91.2
89.7
N.A.
90.6
88.4
84
83.5
N.A.
68.9
N.A.
59.9
67.9
Protein Similarity:
100
N.A.
82
96.4
N.A.
95.3
94.6
N.A.
95.4
94
91
90.7
N.A.
79.3
N.A.
74.8
77.6
P-Site Identity:
100
N.A.
0
100
N.A.
84.6
84.6
N.A.
92.3
76.9
69.2
69.2
N.A.
69.2
N.A.
46.1
6.6
P-Site Similarity:
100
N.A.
0
100
N.A.
92.3
92.3
N.A.
92.3
92.3
84.6
84.6
N.A.
84.6
N.A.
61.5
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.8
58.4
64.3
Protein Similarity:
N.A.
N.A.
N.A.
69.9
71.4
75.8
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
0
14
0
14
0
67
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
27
0
7
0
14
0
60
0
60
0
0
7
% D
% Glu:
0
7
0
40
0
7
0
0
0
14
0
7
0
7
14
% E
% Phe:
0
0
0
0
0
0
67
0
0
7
0
14
67
0
0
% F
% Gly:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
14
14
0
0
7
7
0
0
0
0
7
0
0
% K
% Leu:
0
0
7
0
0
0
0
0
67
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
27
0
7
0
60
0
0
0
0
0
0
0
7
7
0
% N
% Pro:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
27
0
7
7
40
0
0
0
0
0
0
7
0
0
% S
% Thr:
0
20
54
0
0
20
0
60
0
0
14
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
67
% _